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Insulin and Doom


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Doomer
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Post Wed Nov 09, 2011 9:50 am

Insulin and Doom

roccman wrote:Hey Pops!

up until my daughter got diagnosed with Type I Diabetes I may have fallen into the "pack/unpack BOB" shoe box...

now - i hope to hell i am wrong about everything.

you outta post more here!

Hey, Roc

Sorry to hear about your daughter. My step daughter developed type I at age four, it's tough on little kids, even tougher if they grow up to refuse to adopt the regimen, which unfortunately was how she was.

Back then ('70s) pig insulin and pee strips were the height of technology, no time-release insulin analogs like Lantus or pumps or continuous monitoring. You probably know I've never thought we'd move back to the caves anytime soon, that the collapse will be gradual - punctuated, but gradual. I'll guess based on that view recombinant tech will be around a long time.

(Good thing too! Ironically, I developed Type I 2 years ago myself!)
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Post Wed Nov 09, 2011 10:02 am

Re: Doomer defined?

Pops wrote:
roccman wrote:Hey Pops!

up until my daughter got diagnosed with Type I Diabetes I may have fallen into the "pack/unpack BOB" shoe box...

now - i hope to hell i am wrong about everything.

you outta post more here!

Hey, Roc

Sorry to hear about your daughter. My step daughter developed type I at age four, it's tough on little kids, even tougher if they grow up to refuse to adopt the regimen, which unfortunately was how she was.

Back then ('70s) pig insulin and pee strips were the height of technology, no time-release insulin analogs like Lantus or pumps or continuous monitoring. You probably know I've never thought we'd move back to the caves anytime soon, that the collapse will be gradual - punctuated, but gradual. I'll guess based on that view recombinant tech will be around a long time.

(Good thing too! Ironically, I developed Type I 2 years ago myself!)


wow - sorry to hear that Pops

what's your insulin plan look like? assuming a bumpy ride down...

are you stockpiling? how are you refrigerating?
I said to my soul, be still, and wait without hope
For hope would be hope for the wrong thing; wait without love,
For love would be love of the wrong thing; there is yet faith
But the faith and the love and the hope are all in the waiting.

TS Eliot
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Doomer
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Post Wed Nov 09, 2011 1:18 pm

Re: Doomer defined?

I have a couple of years worth of regular and had a couple of years worth of Lantus but over the last few months my T-cells finished off my beta cells and my dose doubled - so I only have one year of Lantus right now. I had been using much less than my original prescription called for so stocking up was easy, it's taking me a little while longer to get back up to the supply I'd like to keep now.

That's figuring a supply with refrigeration of course. But my investigating indicates most insulin looses only 2%/yr effectiveness at 40* which is why the expiration is set at 2 years (it must be 95% potent to meet the rules) - so theoretically at 3 years it would still be 96% potent. Even at ground (root cellar) temperature of 50-55* I'd guess it would only accelerate degradation somewhat and at 2 years be nearly good as new. I'm pretty sanguine about grid reliability for the foreseeable future but if short term outages became a problem in summer I have an old walk-in freezer compressor unit that could be rigged up to the windmill, add lots of insulation and ground source tempering and I think I could keep the temps down in the 40's easily.


Ah ha! Here from my notes:
Lantus was found to meet stability criteria for at least 24 months when stored between 36 and 46°F (2 and 8°C) (Aventis, data on file). Accelerated stability testing at 77°F (25°C) revealed a slight loss in activity by 9 months. Testing at 95–102°F (35–39°C) for 1 month revealed an increase in impurities without loss of activity. Lantus should be stored in a refrigerator to maintain the labeled expiration date. In the absence of refrigeration, unopened vials of Lantus should be discarded after 28 days.


Also, Lantus (which to me is most important because I can easily get by with little to no quickly digestible carbs) also is not tolerant at all to light and freezing kills it dead so that is a big no-no.

Right now I'm using regular that is past expiration (again because my perscription was for much more than I actually needed) and I see no difference in dosage required.


I have lots of syringes (virtually unlimited supply if I reused them till the needle bends) and test strips for maybe a year currently (if I use 3-4 a day) of course in a pinch I'd not be so diligent and wouldn't be quite as concerned about the tightest control possible so I'd only use them periodically to check my fasting sugar to be sure I wasn't way out of control. Strips expire at 2 years so calibrating solution would be good to have or make.


So, I'm not quite done yet! Even if the whole thing came down completely I'd still be around for a couple of years easy.


P.S. here is a good link I found. http://care.diabetesjournals.org/conten ... l.pdf+html
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Post Wed Nov 09, 2011 2:10 pm

Re: Doomer defined?

pretty much along what we are doing Pops.

she does have a pump now - but we have supplies for lantus in the event it gets zapped/no batteries/dropped in the creek etc.

the root cellar is around 50 degrees all year - so that is good.

still - with everything else - this is a major deal - we try not to think about it too much, but it is ever present - every meal - every level check (3 times a day).

is it somewhat rare for us older guys to get it later in life? i don't reall know.

thanks for the link - bookmarked.
I said to my soul, be still, and wait without hope
For hope would be hope for the wrong thing; wait without love,
For love would be love of the wrong thing; there is yet faith
But the faith and the love and the hope are all in the waiting.

TS Eliot
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Doomer
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Post Wed Nov 09, 2011 2:52 pm

Re: Doomer defined?

Yea, it really is big. It's worse when it's your little girl than when it's you.

Only a few percent of people with type I develop it as adults - they call it type 1.5 or LADA (latent autoimmune diabetes of the adult). It's autoimmune just like the kids' version. I tired for about a month, thinking I had a bad case of flu or something, then in a week I really went down, wound up in the ER with a blood glucose of 1400 and bad DKA, doc said I had maybe 1 more day in me and was surprised I didn't do any permanent damage.
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Post Wed Nov 09, 2011 3:19 pm

Re: Doomer defined?

Pops wrote:Yea, it really is big. It's worse when it's your little girl than when it's you.

Only a few percent of people with type I develop it as adults - they call it type 1.5 or LADA (latent autoimmune diabetes of the adult). It's autoimmune just like the kids' version. I tired for about a month, thinking I had a bad case of flu or something, then in a week I really went down, wound up in the ER with a blood glucose of 1400 and bad DKA, doc said I had maybe 1 more day in me and was surprised I didn't do any permanent damage.


wow

glad your still with us!
I said to my soul, be still, and wait without hope
For hope would be hope for the wrong thing; wait without love,
For love would be love of the wrong thing; there is yet faith
But the faith and the love and the hope are all in the waiting.

TS Eliot
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Doomer
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Joined: Thu Dec 30, 2010 1:42 pm

Location: Ozark Plateau

Post Wed Nov 09, 2011 5:35 pm

Doomer defined?

Thanks Roc.
One thing I wanted to add for anyone stumbling across this:

Never ever trust anything you read on the net when it comes to your health! Always follow your doc instructions!
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Post Wed Nov 09, 2011 8:20 pm

Re: Doomer defined?

Pops wrote:Thanks Roc.
One thing I wanted to add for anyone stumbling across this:

Never ever trust anything you read on the net when it comes to your health! Always follow your doc instructions!


Thanks Pops! I think the information you have provided can be helpful, though, to give some people reading an orientation. Maybe I should split the topic and put into Health & Medicine Forum?
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Doomer
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Post Thu Nov 10, 2011 7:32 am

Re: Doomer defined?

Yes, please do.
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www.MyGrandKidsFarm.blogspot.com

Doomer
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Post Thu Dec 01, 2011 12:47 pm

Re: Insulin and Doom

Suggestion: a propane fridge? And a lot of propane?

:(
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